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21+Industry intelligence — not direct nicotine sales
Hardware & Disposables

This popular painkiller may do more harm than good

Summary: Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation.

Key points

  • Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation.
  • A large analysis of clinical trials found that while it does reduce chronic pain, the relief is modest—so small that many patients likely wouldn’t notice much real-world benefit.
  • At the same time, tramadol was linked to a significantly higher risk of serious side effects, especially heart-related problems like chest pain and heart failure, along with common issues such as nausea, dizziness, and sleepiness.

Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation. A large analysis of clinical trials found that while it does reduce chronic pain, the relief is modest—so small that many patients likely wouldn’t notice much real-world benefit. At the same time, tramadol was linked to a significantly higher risk of serious side effects, especially heart-related problems like chest pain and heart failure, along with common issues such as nausea, dizziness, and sleepiness.

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